Capable

(Senior / Principal) Hardware Engineer

San Francisco. Posted 2 months ago

The role

You will provide technical leadership for the physical systems behind the drug-development platform. This includes owning system architecture and hands-on prototyping for automated peptide synthesis, fluid handling, laboratory instrumentation, or subcutaneous drug delivery.

What you will do

  • Own system architecture and technical direction for laboratory-automation or drug-delivery hardware
  • Design and integrate fluidic, electromechanical, sensing, control, and user-interface subsystems
  • Resolve difficult design and integration problems involving flow paths, pressure, sealing, and more
  • Define test strategies, acceptance criteria, and failure-analysis methods
  • Build and debug critical prototypes personally
  • Partner with chemists, biologists, and software collaborators
  • Establish practical engineering standards, documentation, and development workflows

Required qualifications

  • A strong record of owning complex physical systems from ambiguous requirements through working, tested hardware
  • Deep expertise in at least one relevant area: mechanical design, electrical systems, fluidics, controls, automation, medical devices, wearables, implantables, or laboratory instrumentation
  • Exceptional hands-on debugging and root-cause analysis across hardware, controls, process conditions, and experimental outputs
  • The ability to make sound architectural tradeoffs, identify the highest-risk assumptions, and design fast tests
  • Clear technical communication and the ability to lead cross-functional work

Benefits

  • $500+ monthly wellness budget for training, supplements, coaching, recovery, or other tools
  • Medical, dental, and vision coverage options with Capable covering 100% of the base policy
  • Access to HSA, FSA, and 401K plans
  • Healthy vegetarian dinners provided daily

Before you apply

  • Support visa sponsorship where appropriate, including O-1, H-1B, J-1, TN, and other employment-based pathways
  • In-person on site work trial in San Francisco

About the company

Capable Labs is a mission-driven team in San Francisco. The team includes members from MIT, Harvard Medical School, Roche, ETH, and Dana-Farber.