Clera
Computational and Experimental Scientist
New York, Remote. Posted 7 days ago
The role
This person will own computational and experimental work across protein design, laboratory testing, and model improvement. You will close the design-make-test loop by translating sequences into kinetics data to improve designs.
What you will do
- Improve discrete diffusion and companion folding models for peptide and protein design.
- Operate and refine an inference platform.
- Write, debug, and maintain production protocols for liquid-handling robots and plate automation.
- Run BLI and SPR workflows end to end.
- Develop clear protocols for external laboratories and operate internal screening instrumentation.
- Connect receptor biology, protein structure, scoring, and experimental results to identify failure modes.
- Support scientific platform users and customer workflows.
Required qualifications
- 3 to 11 years of relevant experience, including experience in biotech or life sciences software and customer-facing technical or commercial work.
- Hands-on wet-lab experience.
- Background in biology, biochemistry, or a related life science.
- Experience building or operating protein design, protein language, discrete diffusion, or structure prediction models in an experimental design-make-test cycle.
- Practical use of tools such as ESM, ProtT5, RFdiffusion, BindCraft, or equivalents.
- Personally developed and debugged production methods for Hamilton, Tecan, Opentrons, or equivalent liquid-handling platforms.
- End-to-end BLI or SPR kinetic fitting experience, including diagnosing assay and measurement failure modes.
- Python or equivalent scripting skills for automation and kinetic data analysis.
- Understanding of receptor biology, protein structure, and scoring.
- Experience operating inference systems at scale, improving model architectures, and working across experimental biology, bioinformatics, and machine learning.
Benefits
- Equity
- Deal-contingent upside
Before you apply
- Visa sponsorship is not available.
About the company
clera is an early-stage AI-driven biotech company.