Astera

Research Scientist / Engineer, Functional Ultrasound Imaging

Alameda. Posted 3 months ago

The role

You will develop a volumetric functional ultrasound imaging platform for primates by working across hardware, experimentation, and computational analysis. This involves building imaging systems, designing experiments, and analyzing large-scale datasets to create brain atlases.

What you will do

  • Build, validate, and optimize a large-scale volumetric functional ultrasound imaging platform for awake, behaving primates.
  • Design and execute multimodal neuroscience experiments combining fUSI with behavioral paradigms and complementary recording and perturbation techniques.
  • Develop robust computational pipelines for image reconstruction, preprocessing, registration, quality control, statistical analysis, and visualization.
  • Analyze large-scale functional imaging datasets using modern statistical and machine learning approaches.
  • Register imaging data across sessions and animals to generate high-resolution anatomical and functional brain atlases.
  • Integrate fUSI with electrophysiology and other neural recording and perturbation modalities.
  • Collaborate closely with engineers and software developers to improve imaging hardware and acquisition software.
  • Mentor research technicians and, at senior or principal levels, more junior scientists and engineers.
  • Publish scientific discoveries using Open Science and FAIR principles.
  • Contribute to open datasets, software, and technical documentation.

Required qualifications

  • Experience with in vivo functional ultrasound imaging, or with comparable high-resolution neuro imaging technologies.
  • Experience designing and executing neuroscience experiments in primates, including awake macaque fMRI.
  • Strong scientific programming skills in Python and/or MATLAB.
  • Understanding of primate neuroanatomy, image registration, and atlas construction.
  • Experience with image reconstruction and signal processing.
  • Experience analyzing large-scale imaging, electrophysiology, or multimodal neuroscience datasets, including with machine learning or computational neuroscience methods.
  • Ability to work at close quarters with software engineers, hardware engineers, and neuroscientists in a fast-moving, multi-team environment.
  • Track record of mentorship and technical leadership.

Nice to have

  • PhD with 4-12+ years of experience in neuroscience, bioengineering, physics, electrical engineering, or a related field
  • Equivalent demonstrated expertise

Benefits

  • Comprehensive benefits package
  • Total compensation that is competitive and commensurate with the level of experience and qualifications

About the company

Astera is a private foundation on a mission to steer science and technology toward a better future. Astera Neuro seeks to understand and engineer consciousness by combining large-scale neural recording, causal perturbation, and brain-based AI.