General Prism Job Application

The role

This is a general application for various roles within Prism, a program within Radial. Candidates will work on protein motion, structural biology, machine learning, or scientific infrastructure.

What you will do

• Diffraction data processing and structural data pipelines
• Multiconformer and heterogeneity analysis from large datasets
• Data standards work
• Macromolecular ensemble metrics
• Representation learning for protein dynamics
• ML on raw experimental data
• Designing and running campaigns to generate large structural datasets
• Partnering with external collaborators to open and standardize existing datasets
• Scientific data infrastructure, pipelines, and tooling
• Open-source release engineering, reproducibility, and developer experience

Required qualifications

• Familiarity with protein biophysics and the experimental methods that generate structural data
• High agency
• Ability to drive projects and people, including collaborators outside your reporting line
• Comfortable owning a problem end-to-end and unblocking collaborators
• Strong commitment to open science and public-good infrastructure
• Comfort working at the boundary between disciplines
• Bias toward shipping, iteration, and rapid feedback
• Clear written and verbal communication
• Track record of independent work inside collaborative teams

Nice to have

• 3D vision and geometric deep learning backgrounds

About the company

Astera is a private foundation on a mission to steer science and technology toward a better future. Prism is a program within Radial, the basic life sciences division of the Astera Institute.