Genomics
Scientist
London, Remote. Posted a month ago
The role
The Scientist will develop and execute scientific approaches to discover and validate therapeutic targets and develop patient stratification strategies. This role involves mining in-house data using statistical approaches and applying risk tools for patient stratification.
What you will do
- Generate novel therapeutic hypothesis for diseases with unmet need
- Mine in-house data resources using statistical approaches
- Identify and triage potential targets with genetic evidence
- Build understanding of cell types, cellular function, tissue-level characteristics, patient populations and biomarkers
- Apply and optimise risk tools for patient stratification
- Communicate findings to internal and external stakeholders
Required qualifications
- Statistics (modelling, regression)
- Genetics and molecular biology
- Statistical programming (e.g., Python or R)
Nice to have
- Experience using a broad array of statistical genetics approaches (e.g., GWAS, colocalization, fine-mapping, Mendelian randomization, polygenic risk scores)
- Experience defining phenotypes from electronic health records
- Knowledge of Bayesian inference, high dimensional statistics, causal inference
- Experience with software engineering practices (version control [Git & GitHub], testing, documentation, agentic coding, containerisation)
- Experience building and running reproducible pipelines e.g., using WDL, Snakemake, or NextFlow
- Experience using cloud computing and trusted research environments e.g., DNAnexus or Verily Workbench
- Experience with methods development within statistical genetics
Benefits
- Competitive Salary
- Clear Career Path
- Continuous Learning including external courses and a library of L&D materials
- 25 days annual leave, plus bank holidays, plus an extra 3-day company-wide shutdown at year-end
- Market-leading pension scheme
- Comprehensive private health insurance for you and your family with NO excess
- Critical illness and life assurance
- Enhanced paid family leave
- Hybrid Working
- Bank Your Bank Holiday program
- Social culture including Town Halls, team picnics and organised sports events
- Cycle-to-Work scheme
About the company
Genomics is a science-led transatlantic TechBio combining large-scale genetic and health data with proprietary analytics to accelerate drug discovery and advance predictive, preventative healthcare.