Scientist

The role

The Scientist will work within the Life Sciences team to discover and validate therapeutic targets and develop patient stratification strategies. You will develop and execute scientific approaches and communicate findings to internal and external stakeholders.

What you will do

• Generate novel therapeutic hypothesis for diseases with unmet need
• Mine in-house data resources using statistical approaches to understand causal pathophysiology
• Identify and triage potential targets with genetic evidence
• Build understanding of cell types, cellular function, tissue-level characteristics, patient populations and biomarkers
• Apply and optimise risk tools for patient stratification
• Combine genetic information with conventional risk factors to find individuals at risk of disease onset or progression

Required qualifications

• Statistics (modelling, regression)
• Genetics and molecular biology
• Statistical programming (e.g., Python or R)

Nice to have

• Experience using a broad array of statistical genetics approaches (e.g., GWAS, colocalization, fine-mapping, Mendelian randomization, polygenic risk scores)
• Experience defining phenotypes from electronic health records
• Knowledge of Bayesian inference, high dimensional statistics, causal inference
• Experience with software engineering practices (version control [Git & GitHub], testing, documentation, agentic coding, containerisation)
• Experience building and running reproducible pipelines e.g., using WDL, Snakemake, or NextFlow
• Experience using cloud computing and trusted research environments e.g. DNAnexus or Verily Workbench
• Experience with methods development within statistical genetics

Benefits

• Competitive Salary
• Clear Career Path
• Continuous Learning including external courses and a library of L&D materials
• 25 days vacation
• 8 federal holidays
• 3-day company-wide shutdown at year-end
• 401k
• Comprehensive Health, Dental, and Vision plans
• Health Savings Account (HSA)
• Life/AD&D
• Disability coverage
• Bank Your Bank Holiday program

About the company

Genomics is a science-led transatlantic TechBio combining large-scale genetic and health data with proprietary analytics to accelerate drug discovery and advance predictive, preventative healthcare.