Director, Financial Reporting & Technical Accounting

South San Francisco, CA, Remote. Posted a month ago

The role

This senior individual contributor will serve as the technical accounting expert and owner of financial reporting. You will lead the year-end audit, manage complex transactions, and own the 409A valuation and international compliance.

What you will do

Direct the annual audit and financial statement process
Serve as the primary point of contact for external auditors
Own and lead the Disclosure Committee
Prepare financial reporting and accounting content for Executive Leadership Team and Board of Directors
Lead research and author memos on complex and non-routine transactions
Evaluate accounting and disclosures for preclinical and clinical activities
Partner with Corporate Development, Legal, and Strategic Finance on transactions
Liaise with third-party tax advisor regarding tax implications and provisions
Develop, document, and maintain US GAAP accounting policies
Own ASC 718 accounting and reporting

Required qualifications

Bachelor’s degree in Accounting, Finance, or a related field
8–12+ years of relevant experience
Active CPA license
Deep, practical command of US GAAP and financial reporting
Experience with the accounting and disclosures for preclinical and clinical-stage biotech activities
Hands-on experience owning audited financial statements and footnote disclosures
Hands-on experience using Claude and other AI tools to build or improve accounting and reporting workflows

Nice to have

Mix of Big 4 public accounting and public company experience, ideally in biotech or life sciences
Experience accounting for collaboration and licensing agreements with pharma partners
Experience with ASC 718 award modifications and with 409A valuations
Strong familiarity with R&D tax credits, Section 382 analysis, and tax considerations for international equity grants
Experience with statutory reporting, local compliance, and transfer pricing for foreign subsidiaries
Experience at a venture-backed or pre-IPO company, ideally including taking a company through an IPO, and with SEC reporting or designing and implementing a SOX program
Experience with Oracle Cloud ERP, Carta or similar equity systems, and Workiva or an equivalent reporting tool
Advanced Excel and G-Suite skills

Benefits

401(k) plan with employer matching
Medical, dental, and vision coverage
Mental health and well-being support
Open, flexible vacation policy
Paid parental leave (at least 16 weeks for birth parents, 10 weeks for new parents)
Quarterly budget for books and online courses
New hire stipend for home office setup
Monthly cell phone & internet stipend
Access to free onsite baristas and daily lunch for onsite or hybrid employees
Access to a free commuter bus network

About the company

insitro is a physical AI company dedicated to unlocking causal human biology and accelerating the delivery of better medicines to patients. The company uses machine learning and data at scale to decode biology for transformative medicines.