Principal / AD / Director, Agentic AI

The role

This leader will design, build, and adopt agentic AI workflows for small-molecule drug discovery programs. They will also co-lead an initiative to build the Iambic Lab of the Future by integrating AI-driven molecular design with automated experimental workflows.

What you will do

• Lead the technical roadmap and execution for agentic AI workflows.
• Design, build, and deploy multi-step agentic systems integrating ML-based molecular design with automated decision-making.
• Drive efficiency gains in discovery collaborations.
• Co-lead the creation of the Iambic Lab of the Future.
• Partner with computational, experimental, and data engineering teams.
• Represent agentic discovery capabilities externally at conferences and in partnerships.
• Work with senior leadership to develop agentic discovery strategy.
• Develop and mentor a high-performing team.

Required qualifications

• PhD in computational chemistry, machine learning, structural biology, chemical biology, or a closely related discipline; equivalent experience considered.
• 8+ years of experience in drug discovery, ML, or platform-building contexts.
• Demonstrated expertise in designing and deploying AI/ML workflows in a drug discovery or life sciences context.
• Deep familiarity with small-molecule drug discovery including structure-based design, ADMET, and multi-parameter optimization.
• Hands-on experience applying ML models to real discovery programs.
• Proven track record of leading cross-functional scientific teams in a biotech or pharmaceutical setting.
• Experience working within or alongside external research collaborations or partnerships.
• Exceptional scientific communication skills.

Nice to have

• Experience with LLM-based agents, workflow orchestration frameworks, and integration of ML models into laboratory automation pipelines

Benefits

• Company-paid medical coverage
• Flexible spending accounts
• Voluntary life insurance
• 401(k) matching
• Flexible time off
• State-of-the-art facility with a community gym and dining

About the company

Iambic Therapeutics is a technology and clinical-stage life sciences company headquartered in San Diego. The company utilizes molecular superintelligence by integrating proprietary AI with automated, scalable chemistry and biology experimentation.