Sr Associate Scientist I or II, Medicinal Chemistry

The role

The Senior Associate Scientist will design, synthesize, purify, and characterize chemical compounds. This laboratory-based role involves collaborating with medicinal chemists, biologists, and computational researchers throughout the drug discovery process.

What you will do

• Design, synthesize, purify, and characterize chemical compounds using LCMS, HPLC, and NMR.
• Employ individual and automated parallel synthesis approaches.
• Identify and optimize reaction conditions using screening kits and streamlined methodologies.
• Collaborate with the high-throughput experimentation team.
• Analyze biological and ADME-PK data using cheminformatics tools.
• Partner with computational chemists to leverage machine learning insights.
• Present results to project teams and senior leadership.

Required qualifications

• BS in Chemistry with 5+ years experience (pharma/biotech) or MS in Chemistry with 3+ years experience (pharma/biotech)
• Proven skills in multi-step organic synthesis, reaction optimization, SAR analysis, and scientific presentation
• Ability to thrive in a fast-paced, highly collaborative research environment
• Availability to work onsite in San Diego

Nice to have

• Prior exposure to high-throughput experimentation
• Familiarity with ADME-PK principles
• 5+ years of experience contributing to drug discovery projects
• Experience with molecular modeling and structure-based drug design

Benefits

• Company-paid medical coverage
• Flexible spending accounts
• Voluntary life insurance
• 401(k) matching
• Flexible time off
• Community gym
• Dining

About the company

Iambic Therapeutics is a technology and clinical-stage life sciences company headquartered in San Diego. The company utilizes molecular superintelligence by integrating proprietary AI with automated, scalable chemistry and biology experimentation.