Sr. Associate Scientist I / II – High Throughput Chemistry

The role

The Sr. Associate Scientist will execute high-throughput experiments and support compound library campaigns using synthetic chemistry skills. This role works cross-functionally with chemistry, biology, compound management, AI/ML, and software teams using an HTE platform.

What you will do

• Execute parallel synthetic chemistry experiments in support of compound library campaigns.
• Execute and refine standard company procedures and synthetic methods.
• Operate, maintain, and calibrate laboratory automation and analytical/purification equipment.
• Collaborate with senior chemists and cross-functional partners to adapt synthetic routes to automation-compatible processes.
• Record, organize, and analyze experimental and library compound data.
• Communicate results clearly to project teams.
• Ensure all laboratory work follows established safety protocols and ELN data recording.
• Identify bottlenecks in existing processes and contribute to solutions.

Required qualifications

• MS degree in Organic Chemistry with 3+ years of experience or BS in Organic Chemistry with 5+ years of industry experience.
• Strong foundation in modern organic synthetic methods.
• Direct experience with High Throughput Chemistry and/or Parallel Synthesis.
• Familiarity with laboratory automation, liquid handling robotics, and automated analytical/purification systems.
• High adaptability to existing technology.
• Ability to thrive in a fast-paced, highly collaborative, and dynamic research environment.
• Strong written and verbal communication skills.

Nice to have

• Prior hands-on experience with Direct-to-Biology (D2B) strategies for drug discovery.
• Familiarity with the principles of medicinal chemistry.

Benefits

• Company-paid medical coverage
• Flexible spending accounts
• Voluntary life insurance
• 401(k) matching
• Flexible time off
• Community gym
• Dining

About the company

Iambic Therapeutics is a technology and clinical-stage life sciences company headquartered in San Diego. The company utilizes molecular superintelligence by integrating proprietary AI with automated, scalable chemistry and biology experimentation.