Senior / Executive Medical Director, Clinical Development (Oncology)

The role

This person will provide medical and clinical development leadership for an early-stage oncology portfolio. They will own clinical strategy and execution from IND-enabling activities through first-in-human and early efficacy studies.

What you will do

• Serve as the clinical/medical lead for early-stage oncology programs.
• Author and drive clinical components of IND submissions.
• Support and participate in health authority interactions.
• Design first-in-human and early-phase oncology trials.
• Provide ongoing medical monitoring and safety oversight for active trials.
• Partner with translational science and AI/ML platform teams.
• Engage key opinion leaders, investigators, and study sites.
• Collaborate cross-functionally with Regulatory Affairs, CMC, Clinical Operations, Biostatistics, and Program Management.
• Contribute to portfolio-level decisions and business development/due diligence.

Required qualifications

• M.D. or D.O. (or international equivalent)
• Meaningful drug-development experience in biotech or pharma.
• Direct, hands-on experience authoring and executing IND submissions.
• Direct experience designing and running Phase 1 / early-phase oncology clinical trials.
• Demonstrated experience with oncology assets and understanding of the oncology therapeutic and drug-development landscape.
• Working knowledge of GCP, ICH guidelines, and the global regulatory environment for oncology development.

Nice to have

• Board eligibility/certification in hematology/oncology or medical oncology
• PharmD and relevant oncology and clinical experience
• Experience with small-molecule oncology programs and targeted therapies
• Experience taking a program from candidate nomination or IND through clinical proof-of-concept
• Comfort working in a fast-paced, data-rich, technology-forward environment and collaborating with computational and platform teams
• Prior experience presenting to health authorities and/or supporting BD due diligence

Benefits

• Company-paid medical coverage
• Flexible spending accounts
• Voluntary life insurance
• 401(k) matching
• Flexible time off
• Community gym
• Dining

About the company

Iambic Therapeutics (Nasdaq: IAM) is a technology and clinical-stage life sciences company headquartered in San Diego. The company utilizes molecular superintelligence to address the totality of drug discovery and development.