Latchbio
AI Biologist - Neuroscience
San Francisco (preferred), Remote. Posted 13 days ago
The role
You will act as a scientific authority to test if AI agents can reason like expert neuroscientists. You will build tasks and datasets for benchmarks across normal nervous-system function and disease by working with software engineers and neuroscientists.
What you will do
- Define expert reasoning for research questions and write gold-standard answers
- Design realistic research scenarios from hypothesis to inference
- Curate multi-modal data bundles
- Pair basic-science and disease tasks to test transfer of understanding
- Partner with software engineers to turn judgment into new workflows
- Test whether agents choose the right model system and unit of analysis
- Adjudicate contested claims in the literature
- Interrogate agent reasoning step by step
- Pinpoint where agents go wrong
- Score agent confidence
Required qualifications
- PhD or MD/PhD in neuroscience or a closely related field
- Hands-on neuroscience research experience with first-hand data analysis and a publication record
- Direct experience analyzing raw data in at least two modalities: electrophysiology (patch-clamp, MEA, Neuropixels), optical imaging, EEG/sEEG, neuroimaging, single-cell or spatial omics, neuropatholog
- Deep expertise in at least one area (systems/circuit, cellular/molecular, clinical/translational, or computational neuroscience) and working fluency across system levels
- Strong command of experimental design and statistics
- Proficiency in AI agent use
- Confidence to overrule an AI agent when the evidence demands it
- Ability to calibrate confidence and communicate uncertainty
- Practical understanding of model systems (iPSC neurons, organoids, rodents, NHP, human cohorts)
Nice to have
- Familiarity with core resources: Allen Brain Cell Atlas/BICAN, DANDI/NWB, OpenNeuro/BIDS, IBL, ADNI, PPMI, UK Biobank, ClinVar/gnomAD
Benefits
- Health, dental, vision: 100% covered for you, 50% for dependents
- 401(k) (no match)
- PTO: 12 days to start, more as you’re promoted
- Catered lunch and dinner and unlimited snacks (onsite)
- Company outings most months, team off-sites, and a community
Before you apply
- We sponsor H-1B (new and transfers), O-1, and TN, and support STEM OPT
- If your profile matches, we’ll send you a take-home project
- Background check, once you accept
About the company
Latch builds rigorous scientific benchmarks for AI agents across biology. They work with frontier labs and pharma to measure whether agents can handle real biological workflows.