AI Biologist - Genetic Medicines

The role

You will contribute to the technical approach for evaluating AI agent performance across the genetic medicines pipeline. This includes designing case studies, evaluating preclinical data, and reviewing agent outputs for scientific soundness.

What you will do

• Designing realistic program case studies spanning target validation, drug design, screening, and IND-enabling studies
• Evaluating PK/PD, immunogenicity, and GLP toxicology findings
• Reconstructing program go/no-go decisions from multi-source data
• Reviewing and stress-testing agent outputs for scientific soundness
• Calibrating AI agent confidence on preclinical data

Required qualifications

• Advanced degree (MS/PhD/PharmD) in molecular biology, genetics, gene therapy, or a related biomedical field, or equivalent industry experience
• 3+ years of hands-on experience in gene therapy, gene editing, or RNA therapeutics (ASO/siRNA/mRNA) discovery or development
• Direct experience with drug design, drug screening, delivery optimization, or IND-enabling study design in at least one genetic medicine modality
• Experience interpreting on-/off-target editing data, biodistribution, immunogenicity, and GLP toxicology to inform dose selection and risk assessment
• Experience evaluating potency, specificity, and developability trade-offs across vector, construct, or oligonucleotide candidates
• Strong scientific writing skills
• Proficiency in AI agent use
• Comfort operating in uncertainty
• Works with high agency and initiative

Nice to have

• Familiarity with IND-enabling regulatory requirements and the nonclinical data package expected by FDA/EMA

Benefits

• Health, dental, vision: 100% covered for you, 50% for dependents
• 401(k) (no match)
• PTO: 12 days to start, more as you’re promoted
• Catered lunch and dinner (onsite)
• Unlimited snacks (onsite)

Before you apply

• We sponsor H-1B (new and transfers), O-1, and TN, and support STEM OPT
• If your profile matches, we’ll send you a take-home project
• Background check, once you accept

About the company

Latch builds rigorous scientific benchmarks for AI agents across biology. They work with frontier labs and pharma to measure whether agents can handle real biological workflows.