(Senior) RA, Chemistry

The role

The candidate will conduct chemical synthesis, chromatographic purification and biochemical validation of peptides, oligonucleotides and oligo-peptide conjugates. This role supports various drug discovery projects within multidisciplinary teams.

What you will do

• Perform peptide synthesis on automated synthesizers (Multi Pep, Liberty Prime)
• Perform HPLC purification and MS analysis of synthesized products
• Perform in vitro biochemical assays with peptides, oligonucleotides and proteins
• Maintenance of chemistry instruments and supplies

Required qualifications

• Experience with solid phase peptide synthesis and downstream processing (cleavage, deprotection and purification)
• Experience with performing in vitro biochemical assays
• Motivated and proactive with strong problem-solving skills
• Ability to multitask and manage several projects simultaneously
• Team-oriented and open to collaboration across scientific disciplines

Nice to have

• Direct experience with automated peptide synthesizers (Multi Pep and Liberty Prime)
• Experience with high-throughput screening
• Previous experience with solid phase oligonucleotide synthesis, purification and conjugation

About the company

Nosis Bio is a well-funded biotech startup focused on cell-specific delivery of RNA therapeutics. The team consists of biologists, chemists, and machine learning experts.