Scientist (Cell & Tissue Operations)

The role

The Scientist I will run hands-on cell and tissue culture work, including processing human tissue and building cell banks. This role splits time between executing partner studies and strengthening systems like SOPs and cell inventory.

What you will do

• Process human lymphoid tissue and primary cells into single-cell suspensions and organoid cultures
• Apply donor acceptance criteria and track donor metadata
• Optimize and troubleshoot scientific protocols
• Execute partner study protocols under aseptic technique
• Cryopreserve, thaw, and recover primary human cells
• Execute cell banking runs with full chain of custody
• Maintain the LN2 inventory
• Execute flow cytometry for immunophenotyping and study endpoint measurements
• Execute functional assays such as ELISA, MSD, ELISpot, or cytotoxicity
• Analyze data and contribute to study summaries for partners

Required qualifications

• PhD in immunology, cell biology, bioengineering, or a related field with 0–2 years of postdoctoral or industry experience; or an MS with 5+ years of relevant industry experience; or a BS with 8+ years
• Hands-on proficiency in primary human cell or tissue culture under strict aseptic technique
• Hands-on proficiency in cryopreservation: freezing, thawing, and tracking cell stocks
• Hands-on proficiency in flow cytometry, plus at least one other immune assay method (e.g., ELISA, MSD, ELISpot, Luminex)
• Strong documentation habits grounded in data integrity (ALCOA+) principles
• Collaboration across two teams and shifting between study execution and process work
• High standards for data quality and data integrity
• Strong written and verbal skills, critical thinking and rational experimental design capabilities, and clear data presentation skills
• Ability to wear a tight-fitting respirator (e.g., N95 or half-face air-purifying respirator)
• Work with human-derived tissue and cells at BSL-2, including bloodborne pathogen training
• Ability to stand at the bench or biosafety cabinet for extended periods
• Ability to lift up to 25 lb

Nice to have

• Secondary lymphoid organ biology, organoid, or 3D culture experience
• Formal cell banking (MCB/WCB) with release testing such as sterility, mycoplasma, and identity
• Spectral or high-parameter flow cytometry (15+ colors)
• iPSC culture or stem cell-derived immune models
• Plate-based, higher-throughput workflows or liquid handling automation
• SOP authoring in a GLP- or GMP-aware environment

Benefits

• Medical, dental, and vision coverage
• 401(k)
• paid time off
• Hepatitis B vaccination is offered

About the company

Parallel Bio is building a human-first drug discovery platform powered by organoids and AI. The company uses real human biology to improve translational success rates in drug discovery.