Executive Medical Director (Retina Program)

The role

The Executive Medical Director will design, execute, and analyze clinical trials in the ophthalmology therapeutic area. This role reports to the CMO and involves leading Phase 1 retina clinical trials and biomarker strategies.

What you will do

• Serve as clinical lead for Phase 1 retina clinical trials
• Maintain accountability for study execution, data interpretation, and clinical readouts
• Serve as medical monitor for assigned studies
• Lead cross-functional study teams
• Lead development and implementation of biomarker strategies
• Collaborate with research and translational teams to integrate biomarkers into trials
• Serve as primary clinical author of development plans, protocols, IBs, INDs, and CSRs
• Lead clinical contributions to IND submissions and regulatory interactions
• Organize and lead scientific advisory board meetings
• Collaborate to identify program risks and implement mitigation strategies

Required qualifications

• Medical Degree (M.D.) or other degrees considered with relevant experience
• Residency training in Ophthalmology
• 10+ years of clinical ophthalmology research in the biopharmaceutical industry
• Experience with medical monitoring and oversight of Phase 1 retina clinical trials
• Experience with gene therapy clinical studies
• Experience in other phases (Phase 2, 3) of clinical research
• Experience with NDA/BLA/MAA submission planning and execution
• Experience in data analysis, data interpretation, and medical writing
• Knowledge of ICH-GCP and FDA regulatory guidelines
• Knowledge of international regulatory guidelines
• Effective written and verbal communication skills, including public speaking

Nice to have

• Subspecialty training in retina
• Board certification
• Retina fellowship training

About the company

4DMT is a late-stage biotechnology company advancing durable and disease-targeted therapeutics. The company's lead product candidate 4D-150 is designed for the treatment of blinding retinal vascular diseases.