Sr. Clinical Supply Chain Manager

The role

The Sr. Clinical Supply Chain Manager is a senior study supply lead responsible for the strategy, start-up, execution, and lifecycle management of global clinical supplies. This role translates protocol and regulatory assumptions into executable supply strategies and leads multiple global study start-ups.

What you will do

• Own the clinical supply workstream for complex global study start-up.
• Build and maintain integrated start-up plans covering demand, manufacturing, and distribution.
• Assess protocol design and its impact on supply.
• Define supply readiness criteria and drive decisions across study teams.
• Lead supply scenario planning for various material changes.
• Develop and own end-to-end supply strategies for investigational products and ancillary materials.
• Create demand forecasts and supply plans.
• Optimize inventory and resupply parameters.
• Provide business ownership for clinical supply aspects of IRT design.
• Oversee global depot and distribution strategies.

Required qualifications

• Bachelor's degree in supply chain, life sciences, pharmacy, or a related discipline
• Minimum 8 years of progressive experience in clinical supply chain, clinical operations supply, or a closely related discipline within biotechnology or pharmaceuticals
• Substantial sponsor-side experience and demonstrated ownership of end-to-end clinical supply activities
• Proven experience leading at least one complex, global Phase 3 study start-up through supply readiness
• Demonstrated expertise in demand forecasting, packaging and labeling, IRT supply design and UAT, global distribution, depot strategy, import/export, inventory and expiry management, accountability, re
• Working knowledge of cGMP, GDP, GCP interfaces, FDA and EMA expectations, and international clinical supply requirements
• Experience selecting and governing external partners, managing budgets and contracts, resolving complex deviations or supply disruptions, and presenting risk-based recommendations to senior stakeholde
• Advanced project leadership, analytical, communication, negotiation, and problem-solving skills
• Proficiency with IRT, demand-planning and inventory data, and Microsoft Excel and PowerPoint

Nice to have

• Advanced degree or relevant professional certification
• 4 years of experience working with IRT
• Experience with multi-country, blinded, comparator-controlled, cold-chain, biologic, or advanced-therapy studies
• Experience with GMO requirements and APAC, European, and other global markets
• Experience creating dashboards or portfolio-level supply reporting

Before you apply

• All agency inquiries are vetted through 4DMT’s internal Talent Acquisition team.
• No unsolicited resumes will be accepted.

About the company

4DMT is a leading late-stage biotechnology company advancing durable and disease-targeted therapeutics. The company's lead product candidate 4D-150 is designed to provide multi-year sustained delivery of anti-VEGF biologics.