Scientist I, Drug Product Analytics (Laboratory Automation)

The role

This scientist will design, develop, program, and deploy automated analytical methods on Hamilton liquid handling platforms. The role focuses on automating the multiplexed immunoassay suite and supporting drug product development.

What you will do

• Design, develop, program, and deploy automated analytical methods on Hamilton liquid handling platforms
• Program, script, and troubleshoot automated methods in Hamilton VENUS software
• Execute routine and non-routine analysis of internal release, development, and stability samples
• Automate, execute, optimize, and improve the internal multiplex immunoassay (MSD) assay suite
• Support analytical comparability assessments including study design, execution, and statistical data analysis
• Contribute to method development, qualification, and technology transfer activities
• Author and review technical documentation including assay protocols, SOPs, and reports
• Support Vaxcyte PCV and VAXA1 programs through cross-functional collaboration

Required qualifications

• PhD with 0-2 years of relevant industry experience, MS with 5+ years, or BS with 8+ years
• Hands-on experience developing and programming methods on automated liquid handling platforms
• Demonstrated programming and scripting ability (e.g., Hamilton VENUS, Python, VBA, or equivalent)
• Hands-on experience developing, optimizing, and executing ELISA or multiplex immunoassays
• Experience supporting or leading method transfer, method bridging, or comparability assessments
• Familiarity with plate-based assays (Lowry, BCA, etc.) and multiplexed immunoassays (MSD)
• Experience analyzing and visualizing assay data using software tools such as Excel, Prism, or equivalent
• Experience authoring analytical technical documentation and maintaining electronic laboratory notebooks (eLN)
• Strong organizational skills to manage multiple projects and shifting priorities
• Strong interpersonal and communication skills
• Detail-oriented with high scientific rigor and excellence in data integrity

Nice to have

• Hamilton (VENUS software) experience
• Experience with Tecan, Beckman, or comparable systems
• MSD experience
• Practical experience analyzing and characterizing biomolecules (proteins, polysaccharide conjugates, vaccines)
• Experience with vaccines and adjuvant-containing formulations

Benefits

• Comprehensive benefits
• Equity component

About the company

Vaxcyte is a clinical-stage vaccine innovation company engineering high-fidelity vaccines to protect humankind from bacterial diseases.