Engineer II, Conjugation Development and Manufacturing

The role

This individual will contribute to the development, scale up, and manufacturing of multi valent polysaccharide based conjugate vaccines. The role supports both laboratory development and cGMP manufacturing activities.

What you will do

• Operation and maintenance of laboratory equipment, including chemical reactors, TFF systems, HPLCs, and plate readers.
• Support the design and execution of development studies to optimize and characterize conjugation processes.
• Provide technical oversight during cGMP production campaigns.
• Review executed protocols and batch records for accuracy, completeness, and compliance.
• Serve as a subject matter expert for conjugation related activities on project teams.
• Contribute to facility and equipment design considerations to support process scale up and manufacturing readiness.
• Participate in the development of conjugation processes for pipeline programs.
• Maintain accurate and complete documentation in laboratory notebooks or electronic systems.
• Engage in technical discussions and contribute to data interpretation and decision making.
• Collaborate effectively within a team environment to support departmental and program objectives.

Required qualifications

• PhD with 2-5 years of experience in Chemical Engineering, Biochemical Engineering, Chemistry, Biology, or a related discipline
• MS with minimum of 7 years of experience in Chemical Engineering, Biochemical Engineering, Chemistry, Biology, or a related discipline
• BS/BA with minimum of 10 years of experience in Chemical Engineering, Biochemical Engineering, Chemistry, Biology, or a related discipline
• Practical experience with bioprocess operations at bench, pilot, or manufacturing scale.
• Strong working knowledge of cGMP principles and their application in bioprocess environments.
• Foundational understanding of engineering principles relevant to bioprocess development and scale up.
• Proficiency with standard software tools, including Excel, Word, PowerPoint, Visio, and JMP.
• Demonstrated ability to work in cross functional teams and manage multiple concurrent activities.
• Excellent written and verbal communication skills.

Benefits

• Comprehensive benefits
• Equity component

About the company

Vaxcyte is a clinical-stage vaccine innovation company engineering high-fidelity vaccines to protect humankind from the consequences of bacterial diseases.