BioMedical AI Research Engineer

The role

You will design and deploy agentic AI systems that reason over biomedical knowledge, plan multi-step analyses, and integrate scientific data sources. The work supports therapeutic discovery within the company's discovery workflows.

What you will do

• Design and implement agentic AI architectures for multi-step reasoning, planning, and tool use in biomedical contexts
• Develop LLM-based agents that retrieve, rank, and synthesize knowledge from literature, knowledge graphs, omics datasets, and clinical data
• Build memory and feedback mechanisms so agents refine hypotheses and adapt to new data
• Integrate external tools such as analysis pipelines, simulation engines, statistical models, and databases into agent workflows
• Architect scalable systems that combine structured and unstructured biomedical data in production AI environments
• Collaborate with computational biologists, translational scientists, and software engineers to embed systems in discovery pipelines
• Evaluate robustness, reliability, and interpretability of autonomous systems in high-stakes biomedical settings

Required qualifications

• Degree in Computer Science, Machine Learning, Computational Biology, Biomedical Informatics, or related field
• Strong hands-on experience with large language models, including fine-tuning, alignment, and structured prompting
• Experience building agent-based systems or complex LLM orchestration frameworks
• Proficiency in Python and modern ML frameworks (PyTorch, JAX, TensorFlow)
• Experience working with large-scale biomedical datasets (genomics, transcriptomics, clinical records, or scientific corpora)

Nice to have

• Experience designing autonomous research assistants or AI systems that perform multi-step scientific reasoning
• Familiarity with knowledge graphs, hybrid symbolic-neural systems, or multimodal foundation models
• Understanding of privacy, security, and regulatory considerations in healthcare AI

Benefits

• Competitive compensation and benefits package
• Base salary, bonus, and equity
• Open, flexible, and friendly work environment
• Platform to develop long-term careers
• Summary of Benefits available to all applicants

Before you apply

• Xaira Therapeutics does not accept agency resumes; unsolicited agency resumes are not covered by fees

About the company

Xaira is an AI-focused biotech startup developing generative AI models to design protein and antibody therapeutics and foundation models for biology and disease. It is headquartered in the San Francisco Bay Area, Seattle, and London.