Senior Software Engineer, X-Scientist

The role

You will build backend systems, APIs and tool-calling infrastructure that connect AI models to scientific tools, datasets and analysis workflows. You will work with AI scientists, engineers and drug discovery experts on the X-Scientist team.

What you will do

• Build backend systems and APIs that connect AI models to scientific tools, datasets and analysis workflows
• Build tool-calling infrastructure, CLIs, SDKs and workflow runners used by scientists and ML researchers
• Build agentic interfaces where users run analyses, inspect intermediate steps and iterate on results
• Add observability and testing for long-running workflows that call external tools and produce scientific outputs
• Design reliable systems for long-running, multi-step workflows with strong testing, logging and maintainability
• Work with scientific and technical teams to turn complex research workflows into usable, extensible software

Required qualifications

• Strong Python engineering fundamentals, with clean, typed, tested, maintainable code
• Experience building at least one of: a production library, CLI, API, SDK, backend service, workflow system or developer platform
• Familiarity with LLM application development, agent frameworks, tool calling, MCP-style interfaces or orchestration systems
• Comfort working with complex systems that combine multiple components, external calls, domain-specific logic and evolving user needs
• Good instincts for abstraction, error handling, reliability and designing software that can grow across use cases
• Strong communication skills and ability to work in a collaborative, multidisciplinary environment

Nice to have

• Background or interest in computational biology, bioinformatics, protein design, single-cell genomics, biomedical AI or adjacent domains
• Familiarity with biomedical databases or tools such as PubMed, UniProt, AlphaFold, PDB, DepMap or related resources
• Curiosity about biology and scientific research

Benefits

• Competitive compensation and benefits package
• Base salary, bonus and equity
• Open, flexible and friendly work environment
• Platform to develop long-term careers
• Summary of Benefits available to all applicants

Before you apply

• Xaira Therapeutics does not accept agency resumes

About the company

Xaira is an AI-focused biotech startup developing generative AI models to design protein and antibody therapeutics and foundation models for biology and disease. It is headquartered in the San Francisco Bay Area, Seattle and London.