Senior Scientist, Biology

The role

You will lead lab-based preclinical research in inflammation and immunology. You will design and run in vitro and in vivo studies on disease biology, target validation and lead candidate development, and share your findings with cross-functional teams.

What you will do

• Design, run and analyze in vitro and in vivo studies on disease biology and target validation
• Support lead candidate development for preclinical programs
• Identify knowledge gaps and ask mechanistic questions to guide program direction
• Evaluate novel targets and therapeutic strategies
• Dissociate human and mouse tissues into single-cell suspensions or tissue cultures
• Run immune profiling with high-parameter flow cytometry and molecular tools (ELISA, MSD, Luminex, qPCR, RNAseq)
• Run functional assays such as antigen presentation, immune cell activation, proliferation and suppression
• Turn experimental data into actionable insights
• Communicate findings and recommendations to cross-functional teams

Required qualifications

• PhD in Immunology or a related field
• 3+ years of relevant experience
• Track record of impact through first author publications, posters and presentations
• Hands-on experience with primary human and mouse immune cells
• Strong expertise in flow cytometry, including high-parameter panel design and data analysis
• Proven ability to plan, execute, troubleshoot and interpret experiments independently
• Highly organized and precise record keeping
• Ability to manage multiple workstreams in a fast-paced environment
• Clear communicator who can distill complex data into actionable insights

Nice to have

• Excitement about using AI tools in everyday work

Benefits

• Competitive compensation and benefits package
• Open, flexible and friendly work environment
• Platform to develop long-term careers
• Base salary, bonus and equity
• Summary of Benefits available to all applicants

Before you apply

• Xaira Therapeutics does not accept agency resumes; unsolicited agency resumes are not paid for

About the company

Xaira Therapeutics is an AI-focused biotech startup that uses generative AI models to design protein and antibody therapeutics and foundation models for biology and disease. It is headquartered in the San Francisco Bay Area, Seattle and London.