Scientist, Neurodegeneration

The role

You will act as a scientific lead for a neurodegeneration portfolio to discover and validate therapeutic targets. You will design in vivo studies using rodent models and analyze rodent and human brain tissue.

What you will do

• Act as the scientific lead for a key segment of the neurodegeneration portfolio.
• Design and execute in vivo studies using rodent models of neurodegeneration.
• Process and analyze rodent and human brain tissue.
• Develop and apply quantitative readouts for pathology and disease biology.
• Partner with internal experts and external collaborators or CROs.
• Establish and promote technical and cultural standards for scientific functions.
• Contribute to program strategy and high-level decision-making.
• Maintain rigorous, traceable records and structured data capture.
• Monitor latest neurodegeneration literature to inform research programs.

Required qualifications

• Ph.D. in Neuroscience or a related field.
• 1+ years of post-doctoral or industry research experience focused on neurodegeneration.
• Robust understanding of neurodegenerative disease biology.
• Established publication record in the field.
• Experience presenting findings at conferences or similar scientific venues.
• Practical experience processing and analyzing rodent and human brain tissue samples.
• Practical experience with animal surgeries, behavior, and vascular biology.
• Proficiency in imaging and behavioral analysis techniques.
• Experience working with therapeutic modalities relevant to the Central Nervous System (CNS) such as AAV-based approaches, ASOs, or small molecules.
• Strong quantitative and statistical judgment.
• Ability to work with minimal oversight.
• Ability to work in a fast-moving, high-stakes environment.

Nice to have

• Practical experience with animal surgeries, behavior, and vascular biology.
• Proficiency in imaging and behavioral analysis techniques.
• Exposure to analyzing biological datasets.
• Desire to build expertise in transcriptomics, proteomics, or spatial approaches.
• Basic skills in bioinformatics data processing or programming (e.g., Python or R).
• Interest in working with human post-mortem or biopsy samples.
• Motivation to learn advanced imaging techniques, spatial biology, or high-content quantitative histology.
• Potential for growth and commitment to working in a collaborative team environment.
• Clear and effective communication skills.

About the company

Altos Labs is a company whose mission is to restore cell health and resilience through cell rejuvenation to reverse disease, injury, and disabilities. Exceptional scientists and industry leaders work together to advance this shared mission.