Senior Medical Director, Clinical Development

The role

The Senior Medical Director provides strategic and scientific leadership for late-stage, pivotal clinical programs. This person leads the design, execution, and interpretation of clinical studies and oversees Clinical Development Plans.

What you will do

• Provides strategic medical leadership and oversight for assigned clinical programs
• Leads development and execution of Clinical Development Plans
• Drives study design, protocol development, and interpretation of complex clinical data
• Serves as a core member of cross-functional program teams
• Provides senior-level medical monitoring and guidance
• Leads interactions with external stakeholders including key opinion leaders, investigators, regulatory agencies, and alliance partners
• Oversees preparation of key program documents including protocols, investigator brochures, clinical study reports, regulatory submissions, and publications
• Mentors and provides scientific guidance to junior team members
• Identifies and implements process improvements and best practices

Required qualifications

• MD and Residency Experience Required
• Significant experience in late-stage clinical development and drug development in biotech/pharmaceutical industry
• Ability to travel internationally and domestically (approximately 10%)
• Demonstrated ability to collaborate with cross-functional teams and influence without authority in a matrix environment
• Strong strategic thinking, problem-solving, and decision-making skills
• Proven ability to interpret complex clinical data and translate insights into actionable strategies
• Excellent communication and leadership skills
• Experience interacting with senior stakeholders and external experts
• Access to work in setting that meets all requirements including privacy, reliable internet access, phone, and ability to communicate via video conference

Nice to have

• neurology, endocrinology, or rare disease experience strongly preferred
• Experience mentoring or leading team members preferred

Benefits

• Competitive base pay
• Annual performance-based bonuses
• Equity awards
• Comprehensive benefits package

Before you apply

• Unable to hire employees who reside and/or work in Alaska and Hawaii

About the company

Amylyx is a clinical-stage company focused on post-bariatric hypoglycemia (PBH), Wolfram syndrome, and amyotrophic lateral sclerosis (ALS).