Research Associate II, Pluvinage Lab

The role

You will drive high-throughput antibody discovery in autoimmune neurology and neurodegeneration. You will work across the full experimental workflow including designing constructs, cloning, executing screens, and analyzing discoveries.

What you will do

• Design DNA constructs and protein display libraries
• Perform molecular cloning, sequence verification, and quality control
• Prepare reagents and patient samples
• Carry out antibody discovery and antigen-identification workflows
• Process screening data using established analysis workflows
• Validate antibody–antigen interactions using complementary assays
• Troubleshoot experiments and improve discovery methods
• Keep complete experimental records and maintain organized inventories
• Communicate progress at lab meetings
• Contribute to shared lab operations, equipment maintenance, and protocol training

Required qualifications

• Bachelor’s or master’s degree in molecular biology, biochemistry, bioengineering, immunology, genetics, or a related field, or equivalent relevant laboratory experience
• 2+ years of relevant experience in an academic or industry setting (including independent lab work during your undergraduate studies)
• Hands-on research experience in molecular biology
• Demonstrated ability to execute multistep experimental protocols accurately, use appropriate controls, and maintain clear and complete laboratory records
• Growth mindset to stretch your scientific skillset in a supportive environment, and the awareness to know when to ask for help
• Strong attention to detail and organizational skills, including careful tracking of samples, reagents, and experimental conditions
• Excellent communication skills and the ability to work both independently on established workflows and collaboratively with senior scientists
• Commitment to rigorous, reproducible research and a strong interest in antibody discovery and its diagnostic applications

About the company

Arc Institute is an independent nonprofit research organization at the interface of artificial intelligence and biology. It is based in Palo Alto and partners with Stanford University, UC Berkeley, and UC San Francisco.