Senior Director, Head of Supply Chain

The role

The Senior Director, Head of Supply Chain will build and lead the company's supply chain function. This leader will manage end-to-end clinical supply chain strategy and execution for global Phase 2 and Phase 3 clinical studies.

What you will do

• Lead end-to-end clinical supply chain strategy, planning, and execution.
• Develop integrated supply plans connecting clinical demand, manufacturing, and distribution.
• Partner with CMC, Clinical Operations, Quality, Regulatory Affairs, and Program Management.
• Oversee demand forecasting, supply planning, inventory management, and distribution.
• Lead supply chain input on IRT/RTSM design and supply configuration.
• Develop scenario plans and mitigation strategies for operational disruptions.
• Oversee relationships with external packaging, labeling, logistics, depot, and CDMO partners.
• Build scalable supply chain processes, systems, tools, and governance.
• Provide senior leadership with visibility into supply status, risks, and budget implications.
• Support late-stage development and clinical-to-commercial supply readiness.

Required qualifications

• Bachelor's degree in Supply Chain, Operations, Engineering, Life Sciences, Business, or a related discipline
• 12+ years of progressive supply chain experience in the pharmaceutical or biotechnology industry
• Significant responsibility for clinical supply
• Direct Phase 2 and Phase 3 clinical supply experience
• Experience with complex, concurrent global clinical trials or programs
• Experience in demand forecasting, supply planning, inventory management, packaging and labeling, global distribution, depot strategy, and IRT/RTSM-supported supply planning
• Experience integrating clinical demand with manufacturing, CMC, Quality, Regulatory, and program-level supply plans
• Significant experience managing outsourced clinical supply partners
• Working knowledge of applicable GxP requirements and global regulatory expectations related to clinical supply
• Ability to operate in a hands-on, execution-focused environment

Nice to have

• Advanced degree (i.e. MS, PharmD, PhD or equivalent)
• Experience with drug-device combination products, inhaled therapies, complex delivery systems, or products involving multiple interdependent components
• Experience supporting late-stage clinical development and clinical-to-commercial supply readiness

About the company

Avalyn aims to transform the treatment paradigm for pulmonary fibrosis and other serious, rare respiratory diseases. The company is advancing optimized inhaled formulations of established antifibrotic medicines.