Bioinformatics Scientist – HIV-SOMAL

The role

The Bioinformatics Scientist will address the bioinformatics, scientific computing, and data analysis needs of NIAID Division of Intramural Research investigators. This role involves providing analysis support across genomic and clinical research data and developing production pipelines to support HIV research.

What you will do

• Address bioinformatics, scientific computing, and data analysis needs of users.
• Provide support for somatic and germline variant calling and analysis.
• Provide support for single-cell and bulk gene expression analysis.
• Perform de novo assembly of genomes and transcriptomes.
• Provide programming and troubleshooting support to the Research Technologies Branch.
• Perform computational data analysis on genomic and clinical research data.
• Work with staff on scientific programming and experimental design.
• Contribute to and co-author scientific publications.
• Contribute to the development of a scalable resource for next-generation sequencing and machine learning data support.

Required qualifications

• Ability to obtain and maintain a Public Trust security clearance.
• Minimum of a bachelor’s degree in a related field.
• Four or more years of experience in bioinformatics.
• Two or more years developing and maintaining production bioinformatics pipelines.
• Expert-level proficiency in two of the following: Python, R, C/C++, sh/bash.
• Experience building images using Docker, Podman, or Singularity/Apptainer.
• Expert-level proficiency in one pipeline framework: Snakemake, Nextflow, or CWL/WDL.
• Demonstrated expertise building technical and user documentation for tools, pipelines, and applications.
• Experience building pipelines on-premises using high-performance computing infrastructure.
• Next-generation sequencing analysis skills.
• Statistical modeling skills.
• Scripting skills.

Nice to have

• Experience supporting HIV research, including analysis of HIV sequence data.
• Familiarity with HIV and infectious disease data resources and host–pathogen study designs.
• Experience building pipelines or applications in the cloud using AWS, GCP, or Azure.
• Experience building applications using Django, Flask, RShiny, Electron, Flutter, or React.
• Experience working in a laboratory setting.
• Master’s degree or doctorate.

Benefits

• 100% Medical, Dental & Vision Coverage for Employees
• Paid Time Off and Paid Holidays
• 401K match up to 5%
• Educational Benefits for Career Growth
• Employee Referral Bonus
• Flexible Spending Accounts: Healthcare (FSA), Parking Reimbursement Account (PRK), Dependent Care Assistant Program (DCAP), Transportation Reimbursement Account (TRN)

Before you apply

• Ability to obtain and maintain a Public Trust security clearance.
• Submit a cover letter addressing specific questions regarding datasets, pipelines, programming, bioinformatics areas, life science disciplines, machine learning, organoid data, and HIV data.

About the company

Axle is a bioscience and information technology company that offers advancements in translational research, biomedical informatics, and data science applications. They work with top research organizations including multiple institutes at the National Institutes of Health (NIH).