mRNA Science Co-op

The role

The co-op will assist in screening mRNA sequences and chemical modifications to enhance mRNA quality. This role involves performing in vitro transcription reactions and running biochemical assays to characterize mRNA products.

What you will do

• Maintain and culture mammalian cell lines for mRNA expression studies.
• Perform transfection experiments to evaluate mRNA constructs.
• Conduct protein expression and other biochemical assays to characterize mRNA performance.
• Analyze and interpret experimental results using appropriate data analysis tools.
• Process and evaluate multiple samples with attention to accuracy, consistency, and documentation.
• Collaborate with other teams to support cell-based editing and mRNA evaluation studies.
• Maintain detailed documentation of experiments in the ELN system.
• Adhere to all laboratory safety requirements and procedures.
• Contribute to molecular cloning, DNA preparation, and in vitro transcription (IVT) experiments as needed.

Required qualifications

• Pursuing a BS or MS in Biological Sciences or a related field (Bioengineering, Biochemistry/Biophysics, Cell Biology/Molecular Biology, or similar).
• At least one year of relevant hands-on laboratory experience.
• Experience with mammalian cell culture and aseptic technique.
• Experience with mammalian cell transfection and cell-based assays.
• Strong attention to detail and ability to perform repetitive experimental workflows with consistency and accuracy.
• Proficient in Excel, PowerPoint, and data analysis.
• Experience maintaining a laboratory notebook and following written protocols.
• Highly motivated to learn, with a collaborative mindset, strong organizational skills, and effective communication skills.
• Applicants must be currently enrolled in a degree-granting college or university program and maintain their student status throughout the duration of the co-op.

Nice to have

• Experience with protein expression analysis or related biochemical assays.
• Experience with molecular cloning, plasmid DNA preparation, and in vitro transcription (IVT).
• Familiarity with mRNA biology, gene expression studies, or nucleic acid therapeutics.

About the company

Beam Therapeutics is a biotechnology company committed to establishing the leading, fully integrated platform for precision genetic medicines. The company uses base editing technology to advance a diversified portfolio of base editing programs.