Scientist

The role

The Scientist will drive research for integrating antibodies with new technologies and develop products using orthogonal assays. This role involves assay development, data analysis, and collaboration with cross-functional teams.

What you will do

• Design, develop, and optimize current proximity assays using DNA-conjugated antibodies.
• Perform and optimize experiments including Western blotting, PCR/qPCR, Flow Cytometry, NGS, and cell culture.
• Validate newly developed assays by analyzing results and troubleshooting issues.
• Implement quality control for experimental steps and workflow standardization.
• Analyze experimental data using statistical and bioinformatics methods.
• Maintain accurate laboratory records and experimental documentation.
• Present data and findings in team meetings.
• Collaborate with cross-functional teams to execute experiments.
• Stay current with advancements in single-cell analysis and DNA-conjugated antibody applications.
• Maintain laboratory equipment and follow safety protocols.

Required qualifications

• Ph.D. degree in biological sciences with bench lab experience.
• Extensive experience in PCR including nested & two-step PCR, melt curve analysis, primer design, troubleshooting, additives, gradient PCR, Tm balancing, and multiplex PCR.
• Experience in qPCR experiments including intercalating dyes, TaqMan probes, and multi-gene normalization.
• Experience in antibody pair assays.
• Experience in Western Blot applications.
• Experience in immunoprecipitation assays.
• Experience in Tissue Culture including cell line maintenance, treatments, and lysis.
• Ability to independently test hypotheses, plan experiments, troubleshoot, and propose experimental ideas.
• Strong communication skills (both oral and written).
• Ability to work in a laboratory setting with potential exposure to hazardous chemicals and biological materials.
• Consistent wearing of assigned PPE.
• Ability to sit and/or stand for extended periods.

Nice to have

• Ph.D. in a biological science (e.g. Biochemistry, Molecular Biology, Immunology, Cell Biology, Cancer Biology) with a minimum of 2 years of post-doctoral hands-on relevant bench lab experience.
• Experience in proximity extension assays.
• Experience in designing oligo structures.
• Experience with NGS techniques and library preps.
• Experience with Single Cell Technologies.
• Experience performing Flow Cytometry experiments.
• Computer proficiency including MS Office Suite, Google Docs, and basic coding with R, Python or related applications.

Benefits

• Medical (BCBS) and Dental (Delta Dental) plans paid at 90%
• Vision Insurance
• Life Insurance and Short Term Disability
• Long Term Disability
• Flexible Spending accounts
• 401(k) Plan with 6% match
• Tuition Reimbursement
• Generous PTO package
• Parental Leave
• Pet Insurance
• Employee Assistance Program
• Onsite Subsidized Cafeteria

About the company

Cell Signaling Technology (CST) is a life sciences company founded, owned, and run by active research scientists. The company provides products and services to scientists globally and is committed to achieving net-zero emissions by 2029.