Flagshippioneeringinc
Associate Scientist, Bioanalytical Assays
Cambridge, MA USA. Posted 16 days ago
The role
The Associate Scientist will drive bio-analytical assays for a novel DNA platform. This role involves executing and analyzing bioassays to assess efficacy, safety, and biodistribution of nucleic acid therapeutics in rodents and NHPs.
What you will do
- Execution and analysis of bioassays to assess efficacy, safety and biodistribution of novel nucleic acid therapeutics in rodents and NHPs
- Contribute to scientific and technical perspectives to advance platform development
- Develop, optimize, and execute ligand binding assays to support studies in-house and at CROs
- Effectively communicate experimental findings in oral, written, and visual formats
- Work independently and collaboratively in a multidisciplinary team environment
Required qualifications
- Masters or BS in relevant discipline with 6+ years of industry experience
- Deep expertise in ex-vivo analytical assays such as ELISA, MSD, qPCR, ddPCR, etc.
- Hands-on experience with multi-parameter flow-cytometry, including panel design, compensation, and analysis
- Proficiency in processing tissues and isolation of various cell types (hepatocytes, immune cells etc.) from mice and NHPs
- Strong communication, interpersonal, organizational, analytical, and problem-solving skills
- Demonstrate flexibility in supporting accelerated timelines for in vivo studies
- Ability to thrive in a fast-paced, multidisciplinary, and rapidly growing biotech environment
Nice to have
- Experience with various transfection methods in human and NHP PBMCs
- Prior experience in nucleic acid therapeutics or LNPs
- Experience with histological techniques (IHC/IF, ISH, H&E, etc.) analysis
Benefits
- healthcare coverage
- annual incentive program
- retirement benefits
- broad range of other benefits
About the company
Serif Biomedicines is a privately held, early-stage biotechnology company developing a novel approach to gene therapy. It was founded by Flagship Pioneering, an innovation enterprise that creates and grows life sciences companies.