Flagshippioneeringinc
Research Associate II/Senior Research Associate, LNP Production
Cambridge, MA USA. Posted 12 days ago
The role
This person will design, produce, characterize, and optimize LNP formulations to support preclinical research and the development of genetic medicines. They will work across multiple programs and partners to advance novel delivery vehicles for nucleic acid cargos.
What you will do
- Design, formulate, produce, and characterize LNPs to support preclinical research.
- Execute LNP production across a range of process scales.
- Operate and develop processes using LNP manufacturing and process-development equipment.
- Troubleshoot formulation and process challenges.
- Collaborate with scientists and cross-functional teams to design experiments and interpret results.
- Support the development and implementation of LNP production and characterization workflows.
- Maintain accurate documentation in electronic laboratory notebooks.
- Analyze and communicate experimental results and present findings to teams.
Required qualifications
- BS or MS in chemical engineering, biochemical engineering, pharmaceutical sciences, chemistry, biology, or a related scientific discipline.
- RA II: BS + 2-4 years or MS + 0-2 years of relevant industry or research experience.
- SRA: BS + 5 years or MS + 3 years of relevant industry or research experience.
- Hands-on experience with lipid nanoparticle formulation and production, particularly for nucleic acid cargos such as mRNA, siRNA, or other genetic medicines.
- Experience with a range of LNP processing techniques and equipment including mixers, pumping systems, TFF, and related unit operations.
- Familiarity with common analytical techniques used to characterize LNPs.
- Ability to independently execute experiments, troubleshoot technical challenges, and interpret data.
- Strong organizational, written, and verbal communication skills.
- Ability to prioritize effectively and deliver results in a fast-paced environment.
Benefits
- Healthcare coverage
- Annual incentive program
- Retirement benefits
- Broad range of other benefits
About the company
Mirai Bio is a Flagship-founded biotechnology company delivering genetic medicines. It aims to achieve precise, scalable delivery of diverse nucleic acid payloads to specific cells and tissues.