Staff Computational Biologist

The role

You will design and execute research studies to drive early research of prototype cancer early detection products using cfDNA as biomarker. You will lead the analysis and interpretation of molecular and clinical data and develop bioinformatics pipelines.

What you will do

• Lead the analysis and interpretation of molecular and clinical data in the context of early cancer detection.
• Suggest research hypotheses and areas for potential computational model and assay improvement.
• Plan, scope, and execute associated research in partnership with a multidisciplinary team.
• Develop bioinformatics pipelines to enable high throughput NGS data processing and analysis.
• Collaborate with wet lab scientists to characterize and iterate on experimental methods.
• Provide real-time assessments of assay performance, quality control, and clinical/diagnostic utility.
• Collaborate with the larger team to bring forward the next generation of assays for early cancer detection.

Required qualifications

• PhD degree in computational biology, cancer biology, statistics, bioinformatics, or related quantitative field.
• 6+ years of scientific industry experience applying computational techniques for biological discovery and product development.
• Extensive experience in NGS assay and pipeline development.
• Demonstrated track record of implementing complex workflows for high throughput NGS data processing.
• Strong quantitative reasoning and data analysis skills.
• Strong computational and programming skills, including thorough experience with Python statistical packages (Numpy, Matplotlib, Pandas) or equivalents in other languages like R.
• Excellent oral and written communication skills.
• Ability to work on a cross-functional team.

Nice to have

• Expert knowledge of chromatin biology, liquid biopsy, DNA methylation and their relevance in cancer early detection.
• Extensive experience working with DNA methylation data for biomarker discovery research.
• Experience in developing, applying, and evaluating statistical and/or machine learning algorithms.

Benefits

• Equity
• Cash bonuses
• Medical benefits
• Financial benefits
• Other benefits

About the company

Freenome is an equal-opportunity employer that develops early, noninvasive tests for cancer detection.