Generatebiomedicines
Senior Scientist I, Molecular Virology
Somerville, MA. Posted 4 days ago
The role
This person will design, execute, and oversee research projects focused on viral vector and RNA delivery platforms. They will advance research from in vitro evaluation through in vivo validation to support clinical candidate selection.
What you will do
- Lead molecular virology research.
- Design, execute, and oversee molecular virology and mammalian cell culture experiments.
- Develop and optimize high-throughput screening assays and workflows.
- Analyze and interpret complex datasets to recommend next steps for clinical candidate selection.
- Partner with computational scientists and therapeutic experts to develop and evaluate delivery platforms.
- Maintain accurate, complete, and compliant laboratory records.
- Prepare technical reports, peer-reviewed manuscripts, and scientific content for regulatory filings.
- Provide scientific oversight to research associates and mentor junior scientists.
- Present findings in internal and external project reviews.
- Ensure research activities adhere to institutional biosafety and laboratory compliance requirements.
Required qualifications
- Ph.D. in Virology, Molecular Biology, Microbiology, Biochemistry, or a closely related life science discipline
- 4+ years of relevant postdoctoral training or industry research and development experience in biotechnology or pharmaceuticals
- Hands-on experience in mammalian cell culture, viral propagation, reverse genetics, cloning, site-directed mutagenesis, and recombinant vector design
- Experience with qPCR, ddPCR, ELISA, flow cytometry, Western blotting, and mammalian/microbial transfection methods
- Experience with next-generation sequencing library preparation, CRISPR screening, and basic sequence and data analysis tools
- Demonstrated experience applying agentic platforms and protein design tools
- Proficiency with electronic laboratory notebooks (ELN) and laboratory information management systems (LIMS)
- Strong project management and problem-solving skills
- Clear written and verbal communication
- Demonstrated ability to collaborate effectively across disciplines and present findings to senior leadership
Nice to have
- Experience with lentiviral systems and animal models
Benefits
- Annual bonus
- Equity compensation
- Competitive benefits package
About the company
Generate Biomedicines is a clinical-stage generative biology company pioneering the AI revolution in drug design and development. They integrate machine learning with large-scale experimentation to design proteins with defined biological intent.