Senior Director, Program Team Lead

The role

The Senior Director, Program Team Lead owns integrated program strategy for TIL cell therapy assets from early to late-stage clinical development. This role chairs cross-functional teams and connects clinical, CMC, regulatory, and commercial workstreams into a single plan.

What you will do

• Own the program strategy and vision from early development through registration and commercialization.
• Frame program decisions around clinical probability of success, regulatory path, and commercial value.
• Develop and present strategic options and trade-off analyses to senior leadership.
• Track the competitive landscape in solid tumor oncology and cell therapy.
• Align SME deliverables with overall development strategy.
• Partner with the Program Manager to align domain area strategy and execution plans.
• Own program dashboards and reporting for leadership.
• Serve as the primary strategic voice for assigned programs in governance forums.
• Support due diligence, business development, and investor-related activities.
• Adhere to core values, policies, procedures, and business ethics.

Required qualifications

• Advanced degree (PhD, PharmD, MD, MBA, or equivalent).
• 11+ years in clinical drug development with strong CMC experience in oncology.
• Experience with CGT, especially CAR-T, viral, TIL and other products.
• Working knowledge of the global clinical and commercial landscape in oncology and cell therapy.
• Strong strategic and analytical skills.
• Track record leading cross-functional teams through multiple development phases, including regulatory submissions and health authority interactions.
• Proficiency with program and portfolio management tools and timeline oversight.
• Proven ability to influence senior stakeholders and motivate teams without direct authority.
• Ability to remain in a stationary position for extended periods.
• Ability to move about within an office or remote workspace and exert up to 10 pounds of force occasionally.
• Visual acuity sufficient for preparing and analyzing data, viewing computer screens, and extensive reading.
• Repetitive motion involving wrists, hands, and/or fingers.

Nice to have

• Background in program management, strategy, or portfolio leadership within a biotech setting.
• Experience contributing to commercial launch planning or lifecycle strategy from a development role.
• History of engagement with FDA, EMA, or other health authorities in oncology or cell/gene therapy

About the company

Iovance Biotherapeutics, Inc. is the global leader in innovating, developing, and delivering tumor infiltrating lymphocyte (TIL) cell therapies for patients with solid tumors. The company operates as an end-to-end cell therapy company with centralized U.S.-based manufacturing.