Isomorphiclabs
Research Leader / Senior Scientist (Medicinal Drug Design), Cambridge, MA
Cambridge, MA. Posted 3 months ago
The role
Research Leaders and Senior Scientists will provide scientific expertise and strategic direction for drug discovery projects. They will drive programs from initiation to clinical candidate selection and work with machine learning scientists to enhance the AI platform.
What you will do
- Invent new medicines and drive drug discovery programs to value inflection points.
- Collaborate cross-functionally to support data-driven scientific solutions.
- Represent the company externally with collaborators and CROs.
- Provide strategic input and technical direction to ML platform teams.
- Manage CRO resources and monitor KPIs.
- Generate intellectual property positions.
- Prepare detailed scientific proposals and reports.
- Line manage and mentor a team of 2-4 Medicinal Chemists for some roles.
Required qualifications
- PhD in Medicinal Chemistry, Synthetic Organic Chemistry, or a related technical field, or equivalent industrial experience.
- 8+ / 5+ years of professional experience in a Medicinal Chemistry role within a biotech, pharma or CRO setting.
- Proven track record of project leadership or leading medicinal chemistry efforts on drug discovery projects.
- Familiarity of optimisation of ADME properties.
- Experience of leading a high-performing scientific team for people management positions.
- Experience of driving a problem through structure-based drug design.
- Experience of working with and closely managing CRO resources.
- Strong track record of scientific achievements evidenced by publications, patents, and presentations.
- Excellent communication (written and verbal) and interpersonal skills.
- Track record of creative problem solving with a strong growth mindset and adaptability.
Nice to have
- Experience of successful application of fragment-based drug design approaches.
About the company
Isomorphic Labs (IsoLabs) was launched in 2021 to advance human health by building on and beyond the Nobel-winning AlphaFold system. The company uses AI models to model complex biological phenomena to help design novel molecules and develop innovative medicines.