Clinical Contracts Manager, Cambridge, MA

The role

The Clinical Contracts Manager acts as the primary point of contact for vendor outsourcing and business contracting. This role drives vendor selection, negotiates agreements, and manages contract lifecycle activities across assigned therapeutic areas.

What you will do

• Provide primary outsourcing and vendor management support for clinical development functional areas.
• Lead RFI and RFP processes, analyze proposals, and recommend vendor selection.
• Negotiate and execute complex vendor agreements and Master Service Agreements (MSAs).
• Define and implement vendor assessment criteria and process improvement initiatives.
• Drive negotiations for Clinical Trial Agreements (CTAs) and investigator budgets with clinical sites.
• Partner with Clinical Trial Managers, program teams, and CROs to ensure vendor delivery.
• Assess and integrate potential AI tools to facilitate contract negotiations and management.
• Monitor study progress, vendor deliverables, and resource allocation.
• Negotiate change orders to minimize sponsor risk.
• Identify contractual risks and ensure adherence to FMV standards and regulatory requirements.

Required qualifications

• Bachelor’s degree (BA/BS)
• Minimum 5+ years of experience in clinical outsourcing, contracting, procurement, or finance within a pharmaceutical, biopharma, CRO, or clinical research setting
• In-depth knowledge of clinical trial execution, CRO outsourcing models, and regulatory guidelines (GCP/FDA)
• Oncology and/or Rare Disease experience required
• Ability to independently complete and drive all key responsibilities
• Strong contract negotiation, budget management, and project management skills
• Exceptional written and oral communication skills
• AI-curious mindset
• Strategic and analytical thinker
• Ability to build strong cross-functional relationships

Nice to have

• Degree in Healthcare, Science or Finance preferred

About the company

Isomorphic Labs (IsoLabs) was launched in 2021 to advance human health by building on and beyond the Nobel-winning AlphaFold system. The company uses AI models to accelerate scientific discovery and design novel molecules.