Research Lead (Formulation Sciences), London

The role

You will develop and execute (pre)-formulation strategies for small molecules across the drug discovery and preclinical development lifecycle. You will collaborate with drug design, preclinical, and CMC functions to support multiple projects using external CRO resources.

What you will do

• Develop and execute comprehensive (pre)-formulation strategies for small molecules.
• Design and refine innovative formulation technologies like solid dispersions and co-crystals.
• Develop and interpret stability studies using ICH and ASAP methodologies.
• Implement rigorous in-process controls to ensure product performance.
• Collaborate across multi-disciplinary preclinical teams.
• Author technical reports, protocols, and regulatory submissions.

Required qualifications

• PhD in pharmaceutical science, or a related technical field, or equivalent experience.
• 6+ years of professional experience within a biotech or pharma setting.
• Demonstrated expertise in the development of oral solid dosage forms.
• Demonstrated experience of supporting IND packages.
• Deep technical proficiency in preformulation, manufacturing processes, and the implementation of advanced drug delivery technologies.
• Rigorous understanding of global regulatory guidelines, including ICH and FDA.
• Excellent communication (written and verbal), interpersonal and influencing skills.
• Ability to work effectively in a cross-functional, collaborative team environment.

Nice to have

• Specialised knowledge and practical experience in the development of amorphous dispersions

About the company

Isomorphic Labs (IsoLabs) was launched in 2021 to advance human health by building on and beyond the Nobel-winning AlphaFold system. The company uses AI models to accelerate scientific discovery and design novel molecules.