Senior Director, Product Strategy

The role

The Senior Director, Product Strategy develops and drives integrated product strategy for assigned cardiovascular therapy programs. This leader builds target product profiles, value propositions, and differentiation strategies while partnering with cross-functional teams.

What you will do

• Develop, maintain, and evolve the integrated product strategy for the assigned program.
• Draft and iterate the target product profile, value proposition, and differentiation strategy.
• Partner with Clinical Development and Medical Affairs on trial design and evidence-generation planning.
• Conduct scenario planning and trade-off analyses across indications, lines of therapy, and geographies.
• Maintain perspective on the competitive environment and generate insights.
• Build and maintain the program-level commercial fact base.
• Own key forecast assumptions to support stage-gate decisions and program valuation.
• Prepare decision-ready materials and recommendations for portfolio governance forums.
• Track key performance indicators and impact measures for the assigned program.
• Support business development evaluations and launch-readiness workstreams.

Required qualifications

• Bachelor’s degree from an accredited four-year college or university in a scientific, health, or business discipline.
• 8+ years of experience in biotech, pharmaceutical, or life sciences strategy consulting.
• Direct experience supporting product, portfolio, or asset strategy for late stage clinical programs.
• Demonstrated experience developing target product profiles, value propositions, competitive assessments, or market landscape analyses.
• Proven experience working cross-functionally with R&D, Commercial, Regulatory, and Market Access colleagues.
• Experience leading workstreams through influence without direct authority.
• Strong analytical capability, including hands-on experience with financial modeling, forecasting, and program valuation.
• Strong scientific literacy and working knowledge of clinical development, regulatory pathways, and competitive dynamics.
• Excellent written and verbal communication skills.
• Ability to work on-site four days per week in Princeton, New Jersey.
• Flexibility to travel approximately 10–15% across South San Francisco, Princeton, and Chicago sites.

Nice to have

• Advanced degree (PhD, MD, PharmD, or MBA).
• Experience in cardiovascular preferred.
• Exposure to pre-launch or launch planning, including pricing and reimbursement or evidence-generation strategy development.
• Experience presenting to senior governance and influencing executive audiences.
• Experience mentoring junior team members and coordinating the work of analysts, consultants or matrixed contributors.
• Experience in a fast-paced, entrepreneurial biotech environment, with a strong patient-centric orientation and continuous-improvement mindset.

About the company

Kardigan is a heart health company working to make cardiovascular disease preventable, curable and no longer the leading cause of death in the world. The company has a cutting-edge discovery and translational research platform and a pipeline of late-stage candidates.