Product Manager, AI Platform & Partnerships

The role

The Product Manager serves as the internal product owner for AI projects, leading the roadmap for protein design, foundation models, reasoning models, agents, and infrastructure. This role involves translating AI x biology ideas into internal products and managing relationships with external AI partners.

What you will do

• Define the product vision, roadmap, and success metrics for AI platform capabilities
• Translate internal R&D and AI x biology ideas into concrete requirements
• Run operating cadences that drive decisions and accountability
• Own the strategy for engaging the AI ecosystem and prioritizing partners
• Coordinate cross-functional execution across AI/ML, protein engineering, biology, and platform teams
• Source, qualify, and close new AI partnership opportunities
• Own the quality of all external deliverables including reports, decks, and demos
• Produce executive-ready memos to align internal stakeholders

Required qualifications

• 2-5 years of product management, technical program management, alliance management, or BD experience, with at least part of that in AI/ML or computational product environments
• Bachelor's degree in a technical field (CS, engineering, biology, or related)
• Demonstrated ability to own complex, ambiguous strategic relationships and drive them to concrete value generating outcomes
• Strong working knowledge of modern AI/ML concepts (foundation models, training and evaluation, agentic systems, scaling laws) and how they apply to scientific and industrial problems specific to drug
• Familiarity with biology, protein engineering, drug discovery, or another applied scientific domain
• Exceptional written communication
• Track record of running cross-functional execution in matrixed organizations and shipping on aggressive timelines
• Comfort operating in high-ambiguity, fast-evolving partnerships
• Demonstrated handle of agentic coding skills; e.g. ability to rapidly run analyses / generate figures

Nice to have

• Advanced degree
• Experience building or shipping products at a frontier AI lab, AI infrastructure company, or AI-first startup
• Experience structuring partnership terms in collaboration with BD and legal (data rights, IP, joint roadmaps)
• Public writing, talks, or other evidence of unusually strong communication ability
• Experience scaling a partnership function or building partnership operating processes from scratch

Benefits

• Annual performance-based target bonus
• Stock options
• Comprehensive medical, dental, and vision coverage
• 401(k) plan
• Flexible paid time off and holidays
• On-site gym
• Onsite lunch
• Commuter support

About the company

Manifold Bio is a platform biotechnology company pioneering AI-guided protein design and massively multiplexed in vivo screening. The team works across a full stack of protein engineers, biologists, and computational scientists to pursue programs internally and with pharma companies.