Associate Scientist/Senior Associate Scientist, In Vivo Pharmacology – Study Coordinator

The role

The In Vivo Study Coordinator will own the end-to-end planning, coordination, and execution of preclinical in vivo pharmacology programs. This includes managing study lifecycles, performing dosing and tissue collection, and analyzing data for various drug development programs.

What you will do

• Oversee and execute assays assessing pharmacological activity, biodistribution, and efficacy of test articles
• Manage tissue analysis and oversee transfer and storage of samples from rodent and large animal studies
• Perform test article dosing via various administration routes including IV and IP
• Perform rodent perfusion and tissue collection
• Analyze and interpret data
• Document experiments and present results within the company
• Perform molecular and biochemical assays on tissue samples

Required qualifications

• Bachelor's or Master's degree in Biology, Pharmacology, Biomedical Science, or related field
• 5+ years of hands-on in vivo pharmacology experience in a biotech, pharma, or CRO environment
• Demonstrated experience as a study director, study coordinator, or study lead
• Deep proficiency with in vivo techniques: IV, SC, IP, and PO dosing; submandibular and cardiac bleeds; necropsy; tissue collection and processing
• Experience coordinating multiple concurrent studies across different programs and timelines
• Strong organizational skills and attention to detail
• Excellent cross-functional communication
• Self-motivated and capable of operating independently with minimal supervision

Nice to have

• Experience with humanized or disease mouse models
• Familiarity with NHP study coordination and CRO management
• Familiarity with histology, tissue sectioning, and confocal imaging workflows
• Experience with Benchling or similar LIMS platforms
• Exposure to protein therapeutics and other modalities
• Experience writing detailed study plans, SOPs, and IACUC protocol amendments
• Comfortable with data analysis tools including GraphPad Prism and Microsoft Office

Benefits

• Annual performance-based target bonus
• Stock options
• Comprehensive medical, dental, and vision coverage
• 401(k) plan
• Flexible paid time off and holidays
• On-site gym
• Onsite lunch
• Commuter support

About the company

Manifold Bio is a platform biotechnology company pioneering AI-guided protein design and massively multiplexed in vivo screening. The team works across a full stack of protein engineers, biologists, and computational scientists to pursue programs internally and with pharma companies.