Principal Scientist, Formulation Development

The role

You will lead drug product development from early discovery through late-stage clinical development. You will translate compounds into formulations and scalable manufacturing processes while partnering with multidisciplinary teams and CDMOs.

What you will do

• Lead formulation strategy across programs
• Represent Formulation/Pharmaceutical Development on CMC and multidisciplinary project teams
• Design, oversee, and interpret formulation studies for small molecules and/or ASOs
• Develop phase-appropriate formulations and manufacturing processes
• Partner with Discovery and other functions for preclinical study support
• Drive technical execution with CDMOs and provide scientific oversight
• Author and contribute to technical and regulatory documents including INDs, IMPDs, and NDAs
• Guide scientists and external partners

Required qualifications

• PhD in pharmaceutical sciences, chemical or biochemical engineering, chemistry, or a related scientific discipline
• 8+ years of relevant industry experience
• Deep understanding of physicochemical and biopharmaceutical properties
• Demonstrated experience leading formulation development and manufacturing process development from early-stage work through clinical supply
• Strong scientific judgment
• Excellent communication and interpersonal skills
• Highly organized and detail-oriented
• Self-directed and able to make decisions and take ownership
• Regular use of a computer, devices or other office equipment
• Clear communication
• Occasional movement
• Comfort with screen work, basic hand coordination, and focus

Benefits

• 99% of the premium paid for medical, dental and vision plans
• Company-paid life insurance, AD&D, and disability benefits
• Voluntary plans to personalize coverage
• Dollar-for-dollar 401(k) match up to 6%
• Long-term stock incentives
• ESPP
• Discretionary quarterly bonus
• Extremely flexible wellness benefit
• Generous PTO
• Paid holidays
• Company-wide shutdowns

About the company

Praxis Precision Medicines is a clinical-stage biopharmaceutical company translating genetic insights into the development of therapies for central nervous system disorders. The company aims to develop high impact medicines for patients and families affected by complex brain disorders.