Vice President, Clinical Pharmacology & Pharmacometrics

The role

You will set the enterprise strategy for clinical pharmacology, pharmacometrics, and model-informed drug development. You will lead dose strategy, design clinical pharmacology studies, and represent the company in regulatory interactions. This role involves building and scaling the clinical pharmacology function across the clinical portfolio.

What you will do

• Set enterprise strategy for Clinical Pharmacology, Pharmacometrics, Translational Modeling, and preclinical-to-clinical quantitative integration
• Own dose strategy from first-in-human planning through registrational development
• Lead quantitative development approaches including population PK, PK/PD, and clinical trial simulations
• Design and oversee clinical pharmacology studies
• Partner cross-functionally with Clinical Development, DMPK, Toxicology, and other teams
• Represent Recursion in regulatory interactions and ensure high-quality contributions to regulatory documentation
• Represent Clinical Pharmacology and Translational Modeling in cross-functional program teams and alliance settings
• Build, mentor, and scale a high-performing Clinical Pharmacology and Pharmacometrics function
• Advance the use of AI, automation, and advanced analytics in modeling workflows

Required qualifications

• Advanced degree in clinical pharmacology, pharmacometrics, pharmaceutical sciences, quantitative pharmacology, biomedical engineering, medicine, pharmacy, or a related field
• 15+ years of biotech or pharmaceutical industry experience
• Significant leadership experience in Clinical Pharmacology, Pharmacometrics, Quantitative Pharmacology, or model-informed drug development
• Proven success leading clinical pharmacology strategy across multiple programs from first-in-human through registrational development, submission, and labeling
• Deep expertise in PK, PK/PD, exposure-response, exposure-safety, population PK, PBPK, QSP, dose optimization, dose justification, and model-based clinical trial design
• Experience designing, interpreting, and defending clinical pharmacology studies and analyses for global development and regulatory submissions
• Strong understanding of FDA, EMA, MHRA, PMDA, and ICH expectations

Nice to have

• PhD, PharmD, or MD
• Experience in oncology, rare disease, and/or small molecule development
• Experience applying AI, advanced analytics, or automation in clinical pharmacology

Benefits

• Annual bonus
• Equity compensation
• Comprehensive benefits package

About the company

Recursion (NASDAQ: RXRX) is a clinical-stage TechBio company decoding biology to radically improve lives. It uses an AI-native, end-to-end drug discovery and development platform called the Recursion OS.