Roivantsciences
Principal, Biostatistician
Roivant Sciences, Inc., 1 Pennsylvania Plaza, 54th floor, New York, NY 10119, United States. Posted 5 months ago
The role
The Principal, Biostatistician will own statistical and quantitative work to connect clinical evidence to pipeline decisions. This role involves working directly in trial datasets to identify efficacy signals, safety patterns, and subgroup effects.
What you will do
- Work directly in clinical trial datasets to identify efficacy signals, safety patterns, and subgroup effects
- Build statistical analyses including mixed-effects models, longitudinal models, Bayesian frameworks, subgroup analyses, and sensitivity analyses
- Monitor emerging safety signals and unexpected findings in real time
- Pressure-test clinical assumptions and scrutinize statistical analysis plans
- Execute focused 1-5 day analytical sprints on high-priority questions
- Develop a read of the clinical evidence base for near-commercial assets
- Analyze competitors' trial data regarding endpoints, patient populations, effect sizes, and durability
- Synthesize findings from literature, registries, claims, and proprietary datasets
- Drive selection and integration of data sources like claims, labs, clinical trial data, and genomics
- Help build shared analytical infrastructure across Roivant and Vant companies
Required qualifications
- Advanced degree in biostatistics, statistics, epidemiology, or a closely related quantitative field
- Hands-on fluency with clinical trial data and patient-level datasets
- Deep command of statistical methods including mixed-effects models, longitudinal and repeated-measures analyses, Bayesian approaches, multiplicity adjustment, and sensitivity analyses
- Familiarity with clinical trial design and regulatory statistical frameworks (ICH E9, estimands, SAP development)
- Track record of translating rigorous analysis into decisions
- Able to present complex statistical findings clearly to non-technical audiences, including CEO-level stakeholders
- Intensely curious, resourceful, and motivated
Nice to have
- direct experience in clinical trial statistics
Benefits
- meaningful equity participation
- comprehensive company-sponsored benefits package
About the company
Roivant is a commercial-stage biopharmaceutical company that aims to improve the lives of patients by accelerating the development and commercialization of medicines that matter. The company advances its pipeline by creating nimble subsidiaries or “Vants” to develop and commercialize medicines and technologies.