Schrdinger
Senior Principal Scientist, Medicinal Chemistry
Tokyo. Posted 18 days ago
The role
Lead drug discovery programs by executing medicinal chemistry strategies to deliver high-quality development candidates. Collaborate with global cross-functional teams and computational chemists using a proprietary physics-based platform.
What you will do
- Lead drug discovery programs in effective collaboration with global cross-functional teams
- Execute medicinal chemistry strategies to deliver high-quality development candidates
- Collaborate with computational chemists and modelers on the application of Schrödinger’s computational platform
- Drive continuous improvement and implementation of new strategies for experimental hit-finding capabilities
- Provide strategic and technical expertise to the Medicinal Chemistry team and the broader Therapeutics Group
Required qualifications
- PhD in synthetic organic or medicinal chemistry, or a related field
- At least ten years of drug discovery experience in a pharmaceutical and/or biotech setting
- Demonstrated track record in medicinal chemistry, as evidenced by successful advancement of drug discovery projects to clinical candidate nomination
- Excellent understanding of biology, pharmacology, drug metabolism and pharmacokinetics
- Demonstrated experience and expertise with modern experimental hit-finding techniques
- Extensive experience working with external chemistry teams at CROs
- Business-level proficiency in English and Japanese
Nice to have
- Hands-on experience advancing peptide modality programs
Benefits
- competitive salary
- bonus plan
- mutual-aid retirement plans
- over three weeks of paid vacation time
- numerous company holidays
- parental leave program
- healthcare through our partnership with the Japanese Health Insurance Association
- professional development opportunities including trainings and continuous education support
About the company
Schrödinger is a global scientific organization developing and applying advanced computational technologies to improve human health and quality of life.