Serif
Scientist, In Vivo Pharmacology
Cambridge, MA. Posted 15 days ago
The role
This scientist will execute and oversee in vivo efficacy, biodistribution, and PK/PD studies in rodent models. The role involves performing animal procedures, authoring protocols, and collaborating with multi-disciplinary teams and CROs.
What you will do
- Execute and oversee in vivo efficacy, biodistribution, PK/PD in rodent models
- Contribute to study designs, study planning, and resource allocation
- Perform animal procedures including blood collection, necropsy, tissue harvest, and homogenization
- Perform cell isolation and test article administration through multiple routes
- Author rodent study protocols and contribute to NHP protocols
- Oversee or conduct in vivo rodent studies at contract vivariums and/or CROs
- Establish and maintain relationships with vivarium and external CRO
- Perform dose calculations and prepare dosing formulations
- Coordinate shipment of test articles to CROs and receipt of samples
- Ensure study compliance with IACUC protocols and company policies
Required qualifications
- M.S with 10+ years industry experience, or B.S with 12+ years industry experience
- Proficient hands-on experience in mouse models of immunology, oncology and transgenic reporter models
- Experience in writing IACUC protocols
- Experience performing in-vivo procedures in rodents, including dose preparation and administration of therapeutics and sample collection
- Strong organizational, communication and interpersonal skills
- Ability to thrive in a fast-paced, and rapidly growing biotech environment with changing priorities
- Work independently and collaboratively in a multidisciplinary team environment
Nice to have
- Experience with IVIS acquisition and analysis
- Familiarity with NHP protocols
Benefits
- healthcare coverage
- annual incentive program
- retirement benefits
- broad range of other benefits
About the company
Serif Biomedicines is a privately held, early-stage biotechnology company developing a novel approach to gene therapy. It was founded by Flagship Pioneering.