Associate Scientist II, MSAT

The role

The Associate Scientist II, MSAT will support the execution and maturation of preclinical and clinical-stage manufacturing processes. This role involves performing lab-scale RNA and lipid nanoparticle production and analytical testing to improve process robustness and support scale-up.

What you will do

• Support the execution, continuous improvement, and maturation of Strand’s preclinical and clinical-stage manufacturing processes.
• Perform lab-scale RNA and lipid nanoparticle production and analytical testing.
• Evaluate process improvements, troubleshoot technology transfer and manufacturing challenges, improve process robustness, and support process scale-up.
• Author technical protocols and reports documenting experimental procedures, results, and conclusions.
• Collaborate with Process Development, Analytical Development, Automation, and Quality teams.
• Partner with external technical counterparts to support ongoing tech transfer and manufacturing activities.

Required qualifications

• B.S. or Advanced Degree in Biochemistry, Chemical Engineering or related field
• 2+ years of working experience in RNA and/or LNP process improvement, manufacturing and/or optimization at a biotech
• Experience collecting, analyzing, and interpreting experimental data to evaluate process performance and support technical conclusions
• Experience with process development, scale-up, technology transfer, manufacturing support, and process troubleshooting
• Experience optimizing and troubleshooting enzymatic reactions, chromatographic purification, TFF, and other filtration methods for biologics
• Strong technical documentation and communication skills
• Ability to generate and maintain clear and detailed laboratory records
• Ability to present experimental designs, data interpretation, and conclusions to cross-functional groups

Nice to have

• Experience contributing to process characterization or later-stage development activities
• Familiarity with ÄKTA systems and UNICORN control software
• Hands-on experience with RNA and/or LNP production processes and respective standard analytical methods (UV-Vis Spectroscopy, Gel Electrophoresis, ELISA, DLS, RiboGreen, etc.)

Benefits

• health
• dental
• life
• open PTO
• onsite lunch catering
• commuter support
• work/life flexibility and integration

About the company

Strand Therapeutics is a clinical-stage biotechnology company pioneering programmable mRNA therapeutics. Headquartered in Boston, MA, the company is advancing a pipeline with an initial focus on oncology and autoimmune disease.