Director, Molecular & Cellular Immunology

The role

The Director, Molecular & Cellular Immunology will lead the Molecular & Cellular Immunology team to develop non-viral in vivo CART therapies. This role involves executing in vitro workflows to deepen mechanistic understanding of the Stylus platform and progressing lead programs toward clinic.

What you will do

• Conceptualize in vivo T cell therapeutic product candidates and build molecular designs
• Develop experimental strategies and immune cell-based testing systems to evaluate product candidates
• Work with direct reports to focus experimental design and execution
• Lead, manage, mentor, and develop team of direct report scientists
• Apply immunology expertise in collaborative work with multi-disciplinary team members and external partners
• Communicate scientific concepts, strategies, status updates, and experimental results
• Drive and deliver results with speed and rigor
• Monitor latest literature and technologies to inspire innovation
• Present Stylus data externally as appropriate
• May lead or manage collaborations with external partners

Required qualifications

• PhD in Molecular or Cellular Biology, Virology, Immunology or related field of study with deep Immunology expertise
• 8+ years of post-graduate experience
• Minimum of 5 years of drug discovery experience in the pharmaceutical and/or biotechnology industry
• Proven-track-record of leading programs in immunology, immunotherapy or engineered immune cell therapy from early drug discovery to IND, with experience in CART
• Clear track record of accomplishment such as patents, new initiatives, IND preparation, and publications
• Demonstrated expertise in immune-modulating molecule design and application of design-test-optimize cycles
• Experience managing and developing scientists as direct reports
• Ability to excel in internal and external cross-functional collaborations
• Ability to think critically, extract and synthesize simple principles from complex datasets and communicate them effectively

Nice to have

• Previous experience in the areas of T cell engaging bispecific antibodies and antibody discovery

About the company

Stylus Medicine is developing transformative in vivo genetic medicines to unlock cures. The company combines engineered recombinases with non-viral delivery to specifically encode therapeutics.