Stylusmedicine
Associate Scientist, Automation
Cambridge, Massachusetts, United States. Posted 3 days ago
The role
The Associate Scientist, Automation will build automation capabilities to accelerate the development of gene editing tools. This role supports reagent generation and high-throughput screening workflows for the Genome Sciences & Engineering team.
What you will do
- Develop automation capabilities for reagent generation and high-throughput screening workflows
- Optimize automated workflows for plasmid cloning and RNA generation via in vitro transcription
- Develop and run QC assays to sequence-verify plasmid constructs and assess IVT products
- Partner with screening scientists to automate plate preparation, reagent dispensing, and assay setup
- Coordinate DNA synthesis and reagent orders with external vendors
- Manage raw material, plasmid, and RNA inventories
- Maintain detailed documentation in electronic lab notebooks
- Present findings to other teams and contribute to scientific discussions
Required qualifications
- BS with 5+ years of full-time industry or academic research experience in life sciences, biology, biochemistry, engineering, or a related field
- MS with 2+ years of full-time industry or academic research experience in life sciences, biology, biochemistry, engineering, or a related field
- Experience with automated liquid handling systems (e.g., Biomek, Mantis, Echo)
- Experience with high-throughput laboratory workflows, including method development and troubleshooting
- Proficiency in nucleic acid QC methods, including TapeStation, Qubit, NanoDrop, and qPCR
- Hands-on molecular biology experience, including cloning and RNA production and purification
- Working knowledge of data analysis and information management tools such as Excel, GraphPad Prism, SnapGene, and Benchling
- Experience with laboratory inventory management
- Track record of generating precise, reproducible data and performing rigorous quantitative analysis
- Clear and approachable communication skills
- Exceptionally organized and comfortable managing large sample sets, inventories, and overlapping projects
- Strategic thinker who effectively plans and prioritizes to maximize scientific impact
Nice to have
- experience with flow cytometry is a plus
About the company
Stylus Medicine is developing transformative in vivo genetic medicines to unlock cures. The company combines engineered recombinases with non-viral delivery to specifically encode therapeutics.